![]() Piperonyl ring is found in a number of naturally occurring compounds and possesses enormous biological activities. Furthermore, the molecular docking was performed using the protein Glc-N-6-P synthase to find out the binding affinity and the H-bonding and the findings exhibited that compound-3 possessed the H-bonding with seven amino acid residues of the protein with the binding affinity in the range − 7.6 to − 6.6 kcal/mol. MTT assay was also performed to assess the percent viability of the cells (HepG2), and the findings revealed that the compounds were less toxic in nature and possess the percent viability 95–98% at 3.125 µM. The results revealed that the compounds (1–3) exhibited significant antibacterial potential and strongly recommended the computational results. The bioactive compounds were then synthesized, characterized and screened for antimicrobial effect and the results, were compared, with ciprofloxacin. The structures of the compounds were drawn by Chem Draw Ultra 8.0 and the drug-likeness properties were calculated by molinspiration, the results exhibited that all the compounds were bioactive. The recent study represented, the computational analysis, synthesis, characterization, antimicrobial and molecular docking assessment of three compounds with some important heterocyclic nucleus such as pyrimidine oxazole and pyrazole. ![]() From anĮnvironmental and economic perspective, this biocatalytic method has great application potential, making it a green and This is a cost-effective,Ĭlean and eco-friendly process for the preparation of chiral secondary alcohols compared to chemical processes. Gram scale through catalytic asymmetric reduction using the biocatalyst was the highest report so far. Also, production of (R)-5a in terms of yield and The gram-scale production was carried out, andĩ.70 g of (R)-5a in enantiomerically pure form was obtained in 96% yield. High yield and enantiomerically pure form using L. (R)-1-(benzofuran-Ģ-yl)ethanol 5a, which can be used in the synthesis of pharmaceuticals such as bufuralols potent nonselective β-blockersĪntagonists, Amiodarone (cardiac anti-arrhythmic), and Benziodarone (coronary vasodilator), was produced in gram-scale, Secondary chiral carbinols were obtained by asymmetricīioreduction of different prochiral substrates with results up to > 99% enantiomeric excess (ee). ![]() In this study, Lactobacillus kefiri P2 biocatalysts isolated from traditional dairy products, were used to catalyze theĪsymmetric reduction of prochiral ketones to chiral secondary alcohols. As a result, financial education is required for people to invest their money wisely.Chiral heterocyclic secondary alcohols have received much attention due to their widespread use in pharmaceutical intermediates. But, in the end, every investor wants to maximize returns while also protecting his or her cash. The financial markets nowadays are highly complex, with each investor having unique financial demands based on his or her financial goals and risk appetite. People should be aware of all investment options before making financial decisions. In the investment process, every individual requires good financial planning. The data has been analyzed using SPSS Software by applying Chi-Square Test between different attributes. The information was gathered by an examination of questionnaires distributed to various parts of Delhi-NCR. In the current study, the researcher aims to examine how investors invest and statistically test the interrelationships between various attributes. States with higher investment commitments are more progressive. An economy may enjoy high levels of consumption without investment, but this would result in an unbalanced economy. The flow of capital employed for productive purposes is known as investment. Over the last few years, retail investors' engagement in the equities markets has increased. A developing economy, such as India, requires an increasing flow of savings to business enterprises. The capital market is supported by investors.
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